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Simplified etymology
Anathema entered English in the early 16th century through ecclesiastical Latin, where it meant an excommunicated person or an act of excommunication. It derives from Greek anathēma, originally “something dedicated,” which later developed the senses “something devoted to evil” and “accursed thing.”
Etymology
Borrowed through Late Latin from Greek anathema, originally 'something set up or dedicated,' from anatithenai, 'to set up.' In church Greek it narrowed to something devoted to destruction or formally cursed, producing the modern figurative sense of a thing utterly detested.