Meanings
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1
adj
Unjustly disagreeable, argumentative or objectionable; brazenly rude.
He was an especially obnoxious and detestable specimen of a man.
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2
adj
Exposed or vulnerable to something, especially harm or injury.
[T]he reſidence and the ſingle liuinges of miniſters preſume not onely to annihilate the ſolemne ordinations of ſuch as the Church muſt of force admit, but alſo to vrge a kinde of vniuerſall proſcription againſt them, to ſet dovvne articles to dravv commiſſions, and almoſt to name themſelues of the Quorum for inquirie into mens eſtates and dealings, vvhom at their pleaſure they vvould depriue and make obnoxious to vvhat puniſhment themſelues liſt, […].
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4
adj
And they dreſſed and prepard Hierome of Prage, an oath, in the Councell of Conſtance, by vvhich he muſt ſvveare, freely, voluntarily, (or elſe bee burned) and ſimplie, and vvithout condition, To aſſent to that Church, in all things, but eſpecially in the Doctrines of the Keyes, and Eccleſiaſtick immunities and reliques, and all the ceremonies, vvhich vvere the moſt obnoxious matters.
Thesaurus
PIE word *h₁epi Learned borrowing from Latin obnoxiōsus (“subject to someone, under someone’s authority”) + English -ous (suffix denoting the presence of a quality in any degree, typically an abundance). Obnoxiōsus is derived from obnoxius (“guilty, punishable; subject to someone, under someone’s authority”) + -ōsus (suffix meaning ‘full of; overly; prone to’, forming adjectives from nouns).