Meanings
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1
noun
a book or page format made by folding a full sheet twice to create four leaves, or eight pages
The printer folded each sheet twice to produce a quarto gathering.
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2
noun
a book produced in quarto format
The archive holds the treatise in a slim seventeenth-century quarto.
Thesaurus
Etymology
From Latin in quarto ('in a fourth'), based on quartus ('fourth'). A printer made the format by folding a sheet into four leaves, each leaf being one quarter of the original sheet.