Project Gutenberg #1566
The Evolution of Modern Medicine
William Osler
1921Osler's lectures tracing medicine from antiquity to modern scientific practice, prepared chapter by chapter from Project Gutenberg HTML.
Project Gutenberg #1566 Public domain in the United States Cover source Local typographic cover created for MojiMori from public-domain source metadata
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and those who heal through medicine. Only he who believes can work miracles. The physician has to accomplish that which God would have done miraculously, had there been faith enough in the sick man (Stoddart, p. 194). He had the Hippocratic conception of the "vis medicatrix naturae"—no one keener since the days of the Greeks. Man is his own doctor and finds proper healing herbs in his own garden: the physician is in ourselves, in our own nature are all things that we need: and speaking of wounds, with singular prescience he says that the treatment should be defensive so that no contingency from without could hinder Nature in her work (Stoddart, p. 213).
Paracelsus expresses the healing powers of nature by the word "mumia," which he regarded as a sort of magnetic influence or force, and he believed that anyone possessing this could arrest or heal disease in others. As the lily breaks forth in invisible perfume, so healing influences may pass from an invisible body. Upon these views of Paracelsus was based the theory of the sympathetic cure of disease which had an extraordinary vogue in the late sixteenth and seventeenth centuries, and which is not without its modern counterpart.
In the next century, in Van Helmont we meet with the Archaeus everywhere presiding, controlling and regulating the animate and inanimate bodies, working this time through agents, local ferments. The Rosicrucians had their direct inspiration from his writings, and such mystics as the English Rosicrucian Fludd were strong Paracelsians.(14)
(14) Robert Fludd, the Mystical Physician, British Medical Journal, London, 1897, ii, 408.
The doctrine of contraries drawn from the old Greek philosophy, upon which a good deal of the treatment of Hippocrates and Galen was based—dryness expelled by moisture, cold by heat, etc.—was opposed by Paracelsus in favor of a theory of similars, upon which the practice of homeopathy is based. This really arose from the primitive beliefs, to which I have already referred as leading to the use of eyebright in diseases of the eye, and cyclamen in diseases of the ear because of its resemblance to that part; and the Egyptian organotherapy had the same basis,—spleen would cure spleen, heart, heart, etc. In the sixteenth and seventeenth centuries these doctrines of sympathies and antipathies were much in vogue. A Scotchman, Sylvester Rattray, edited in the "Theatrum Sympatheticum"(15) all the writings upon the sympathies and antipathies of man with animal, vegetable and mineral substances, and the whole art of physics was based on this principle.
(15) Rattray: Theatrum Sympatheticum, Norimberge, MDCLXII.
Upon this theory of "mumia," or magnetic force, the sympathetic cure of disease was based. The weapon salve, the sympathetic ointment, and the famous powder of sympathy were the instruments through which it acted. The magnetic cure of wounds became the vogue. Van Helmont adopted these views in his famous treatise "De Magnetica Vulnerum Curatione,"(16) in which he asserted that cures were wrought through magnetic influence. How close they came to modern views of wound infection may be judged from the following: "Upon the solution of Unity in any part the ambient air . . . repleted with various evaporations or aporrhoeas of mixt bodies, especially such as are then suffering the act of putrefaction, violently invadeth the part and thereupon impresseth an exotic miasm or noxious diathesis, which disposeth the blood successively arriving at the wound, to putrefaction, by the intervention of fermentation." With his magnetic sympathy, Van Helmont expressed clearly the doctrine of immunity and the cure of disease by immune sera: "For he who has once recovered from that disease hath not only obtained a pure balsaamical blood, whereby for the future he is rendered free from any recidivation of the same evil, but also infallibly cures the same affection in his neighbour . . . and by the mysterious power of Magnetism transplants that balsaam and conserving quality into the blood of another." He was rash enough to go further and say that the cures effected by the relics of the saints were also due to the same cause—a statement which led to a great discussion with the theologians and to Van Helmont's arrest for heresy, and small wonder, when he makes such bold statements as "Let the Divine enquire only concerning God, the Naturalist concerning Nature," and "God in the production of miracles does for the most part walk hand in hand with Nature."
(16) An English translation by Walter Charleton appeared in 1650, entitled "A Ternary of Paradoxes."
That wandering genius, Sir Kenelm Digby, did much to popularize this method of treatment by his lecture on the "Powder of Sympathy."(17) His powder was composed of copperas alone or mixed with gum tragacanth. He regarded the cure as effected through the subtle influence of the sympathetic spirits or, as Highmore says, by "atomicall energy wrought at a distance," and the remedy could be applied to the wound itself, or to a cloth soaked in the blood or secretions, or to the weapon that caused the wound. One factor leading to success may have been that in the directions which Digby gave for treating the wound (in the celebrated case of James Howell, for instance), it was to be let alone and kept clean. The practice is alluded to very frequently by the poets. In the "Lay of the Last Minstrel" we find the following:
(17) French edition, 1668, English translation, same year. For a discussion on the author of the weapon salve see Van Helmont, who gives the various formulas. Highmore (1651) says the "powder is a Zaphyrian salt calcined by a celestial fire operating in Leo and Cancer into a Lunar complexion." But she has ta'en the broken lance, And wash'd it from the clotted gore, And salved the splinter o'er and o'er. William of Deloraine, in trance, Whene'er she turn'd it round and round, Twisted, as if she gall'd his wound, Then to her maidens she did say, That he should be whole man and sound, (Canto iii, xxiii.)
and in Dryden's "Tempest" (V, 1) Ariel says:
Anoint the Sword which pierc'd him with the Weapon-Salve, And wrap it close from Air till I have time To visit him again.
From Van Helmont comes the famous story of the new nose that dropped off in sympathy with the dead arm from which it was taken, and the source of the famous lines of Hudibras. As I have not seen the original story quoted of late years it may be worth while to give it: "A certain inhabitant of Bruxels, in a combat had his nose mowed off, addressed himself to Tagliacozzus, a famous Chirurgein, living at Bononia, that he might procure a new one; and when he feared the incision of his own arm, he hired a Porter to admit it, out of whose arm, having first given the reward agreed upon, at length he dig'd a new nose. About thirteen moneths after his return to his own Countrey, on a sudden the ingrafted nose grew cold, putrified, and within few days drops off. To those of his friends that were curious in the exploration of the cause of this unexpected misfortune, it was discovered, that the Porter expired, neer about the same punctilio of time, wherein the nose grew frigid and cadaverous. There are at Bruxels yet surviving, some of good repute, that were eye-witnesses of these occurrences."(18)
(18) Charleton: Of the Magnetic Cure of Wounds, London, 1650, p. 13.
Equally in the history of science and of medicine, 1542 is a starred year, marked by a revolution in our knowledge alike of Macrocosm and Microcosm. In Frauenburg, the town physician and a canon, now nearing the Psalmist limit and his end, had sent to the press the studies of a lifetime—"De revolutionibus orbium coelestium." It was no new thought, no new demonstration that Copernicus thus gave to his generation. Centuries before, men of the keenest scientific minds from Pythagoras on had worked out a heliocentric theory, fully promulgated by Aristarchus, and very generally accepted by the brilliant investigators of the Alexandrian school; but in the long interval, lapped in Oriental lethargy, man had been content to acknowledge that the heavens declare the glory of God and that the firmament sheweth his handiwork. There had been great astronomers before Copernicus. In the fifteenth century Nicholas of Cusa and Regiomontanus had hinted at the heliocentric theory; but 1512 marks an epoch in the history of science, since for all time Copernicus put the problem in a way that compelled acquiescence.
Nor did Copernicus announce a truth perfect and complete, not to be modified, but there were many contradictions and lacunae which the work of subsequent observers had to reconcile and fill up. For long years Copernicus had brooded over the great thoughts which his careful observation had compelled. We can imagine the touching scene in the little town when his friend Osiander brought the first copy of the precious volume hot from the press, a well enough printed book. Already on his deathbed, stricken with a long illness, the old man must have had doubts how his work would be received, though years before Pope Clement VII had sent him encouraging words. Fortunately death saved him from the "rending" which is the portion of so many innovators and discoverers. His great contemporary reformer, Luther, expressed the view of the day when he said the fool will turn topsy-turvy the whole art of astronomy; but the Bible says that Joshua commanded the Sun to stand still, not the Earth. The scholarly Melanchthon, himself an astronomer, thought the book so godless that he recommended its suppression (Dannemann, Grundriss). The church was too much involved in the Ptolemaic system to accept any change and it was not until 1822 that the works of Copernicus were removed from the Index.